Deebo Samuel bullied the Seahawks in a 28-16 victory

Deebo Samuel said that's my bike punk, as he caught 7 passes for 149 yards and two touchdowns, one of them on the ground. Samuel had his second straight game with multiple touchdowns to lead San Francisco (10-3) to the brink of winning back-to-back NFC West titles for the first time since 2011-12.

The Niners lead the Seahawks (6-7) and Rams by four games with four to play and hold the tiebreaker over Seattle. Under Pete Carroll, Seattle has lost four straight games for the first time in 14 seasons and has lost five straight to the 49ers.

Christian McCaffrey had a 72-yard run on the first play from scrimmage for San Francisco to set the tone early. This helped set up a short TD run by Jordan Mason. But Drew Lock answered back with a 31-yard TD pass on the opening drive to DK Metcalf with Metcalf appearing to celebrate with what has become a signature celebration sending a message in sign language. Drew Lock threw two TD passes in his first start since the end of 2021 but couldn't keep up with the high-powered 49ers.

Purdy finished 19 for 27 for a career-high 368 yards with two TDs and one interception and CMC finished with 145 rushing yards on 16 carriers.